Poliomyelitis, commonly known as polio, is a highly infectious viral disease that can cause irreversible paralysis.
Polio mainly affects children under the age of five. Most infected children do not produce symptoms but can still spread the virus and cause potentially fatal cases.
According to the World Health Organization, polio cases have decreased by over 99 percent since 1988 – from an estimated 350,000 cases to 175 by 2019. In 2021, just six cases were reported.
Unless the virus is eliminated it will continue to spread, particularly in conflict zones and other areas where displaced people live in unsanitary conditions; the perfect conditions for the re-emergence and spread of the disease.
Currently, wild poliovirus type 1 affects two countries: Pakistan and Afghanistan.
Supportive therapy can be given but there is no cure for paralysis. However, polio infection is preventable with vaccination and is essential to the global eradication of polio.
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Polio: Key facts
In some cases the virus can also infect the central nervous system, multiply inside nerve cells and destroy them. This leads to paralysis of the limbs, most often the legs. Of those people that develop paralysis from polio up to 10 percent die due to their breathing muscles failing.
Typical symptoms are: fatigue, headaches, vomiting, stiffness of the neck and pain in the limbs. These symptoms often go away on their own and people make a full recovery.
Around one percent of polio cases cause paralysis of the limbs, and sometimes the breathing muscles.
There are two types of vaccine available for prevention: oral polio vaccine (OPV) and the inactivated polio vaccine (IPV). If enough people in a community are immunised, the virus will be deprived of susceptible hosts. This will prevent its spread, causing it to die out.
The oral polio vaccine is easily given, safe and provides potentially life-long protection. It also produces an immune response in the intestine, making it effective in preventing transmission of the virus within communities.
The inactivated polio vaccine is given in four doses as an injection. It is more expensive than the oral vaccine, produces a lower level of immunity, and does not stop transmission from person to person. Oral polio vaccine had therefore been the vaccine of choice in many countries.
However, because the oral vaccine contains attenuated (weakened) polioviruses, on extremely rare occasions, use of OPV can result in cases of polio. For this reason, as soon as a country has eradicated wild polio transmission (polio cases not related to OPV), it is asked to stop using OPV in its routine immunisation programmes.
After the launch of the Global Polio Eradication Initiative (GPEI) in 1988, the objective of which was to achieve a polio-free world, there are two polio-endemic countries left: Afghanistan, and Pakistan.
Weak health systems and infrastructure, conflict and poor sanitation have interfered with the eradication of polio in these countries.
Coordinated immunisation planning and high vaccination coverage is needed to stop the transmission of the virus within these countries and spread of the virus to others. Eradication strategy consists of not only vaccination programmes but also surveillance to find and report cases to be able to monitor potential polio outbreaks and provide immunisations.