Global health review

MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh. Caption
MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh.

A weekly round-up of all the latest global health research from MSF projects and beyond

31 July 2026

Calling all researchers: BMJ Global Health is seeking papers on population mortality in fragile and conflict settings. Head to the MSF Science Portal to find out further details, and to stay up to date with the latest call for submissions across leading journals in humanitarian and global health.

 

This week, MSF research published in BMJ Global Health examined the characteristics of violence, perceived barriers to care, and timely access to care among survivors of sexual violence in North Kivu, the Democratic Republic of the Congo. It demonstrated that increased violence and displacement impact the nature of sexual violence experienced as well as care-seeking behaviour, calling for better awareness raising to support survivors access to care.

 

In Pharmaceuticals, a DNDi article presented a computational tool that helps identify possible new drug targets for Chagas disease. The tool successfully predicted targets for most of the compounds it was tested on, offering a faster and more affordable way to speed up early drug discovery for Chagas disease and other neglected diseases.

 

An MSF article in Open Forum Infectious Diseases looked at outcomes for patients with tuberculosis (TB) resistant to bedaquiline in Uzbekistan. Findings demonstrated that treatment took well over a year on average, with many patients still not being free of TB by the end, underscoring the need for better options as resistance to key TB drugs rises.

 

Finally, a comment with MSF contribution in The Lancet Infectious Diseases argued that MSF's existing Ebola vaccine could offer partial cross-protection against the related Bundibugyo virus, and called for its cautious and carefully monitored use in high-risk groups during the current outbreak.

 

Best regards,

 

Ahmed Abdelghany, Lillian Matthes, and Holly Baker with MSF-authored article assistance from Alys Barton and Amelia Zhao.

 

All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days 2026 conference.

Antimicrobial resistance

The Lancet • Article: Oral step-down, optimal drug, and total duration of antibiotic treatment in African children hospitalised with severe community-acquired pneumonia (PediCAP): a factorial randomised controlled trial

The Lancet • Comment: How long must we treat? A question as old as penicillin
 

Climate change and Planetary Health

The Lancet • Comment: Intersectionality in climate and health equity research

The Lancet Planetary Health • Comment: Mitigating the effects of air pollution on cardiovascular diseases: community-based interventions for risk monitoring and communication

The Lancet Planetary Health • Article: Environmental suitability of Coccidioides in the USA under climate change scenarios: a modelling study

The Lancet Planetary Health • Comment: Plant-based misinformation as a barrier to dietary transition

The Lancet Planetary Health • Article: Pandemic impacts on protected rainforests and rural communities with variable health and livelihood support in West Kalimantan, Indonesia: a mixed-methods approach combining household surveys and remote sensing

 

Conflict, migration and health

The Lancet Planetary Health • Comment: How the Strait of Hormuz is restructuring nutrition in small island developing states
 

Global health

The Lancet Digital Health • Comment: Global health suffers when corporate AI sovereigns reign

The Lancet Global Health • Article: PCR-confirmed Buruli ulcer incidence over a 16-year period in Benin: a nationwide, retrospective, observational study

The Lancet Global Health • Feature: From fragmentation to integration: regional health governance in southeast Asia

The Lancet Global Health • Article: Screening, brief intervention, and referral to treatment compared with treatment as usual for alcohol use in an integrated refugee settlement in Zambia: a hybrid, type 1, randomised controlled trial

The Lancet Global Health • Article: Global, regional, and national prevalence of peripheral arterial disease in 2023: an updated systematic review and modelling study
 

HIV

The Lancet Infectious Diseases • Comment: USA to end support of South Africa's HIV programmes

The Lancet HIV • Feature: Ukraine's HIV prevention supplies hit in Russian strike

The Lancet HIV • Article: 100% committed to life
 

Infectious diseases

The Lancet Infectious Diseases • Article: Efficacy, safety, and acceptability of a child-friendly, chewable formulation of oxantel pamoate versus mebendazole for Trichuris spp infections in children aged 2–12 years in Tanzania: a randomised, single-blind, phase 2 trial

The Lancet Infectious Diseases • Article: Genomic epidemiology of invasive meningococcal disease in Scotland before, during, and after the COVID-19 pandemic: a retrospective observational study

The Lancet Infectious Diseases • Comment: The wider value of RSV prevention

The Lancet Planetary Health • Article: Drivers of sylvatic yellow fever transmission in southeast Brazil: a joint epidemiological and phylodynamic inference

 

Malaria

The Lancet Planetary Health • Review: Climate change and malaria in west Africa: a review of strategies to handle one of the world’s most prominent anthroponoses

Malaria Journal • Article: Malaria diagnosis practices in formal private drug retail shops in the Ho Municipality, Ghana: a cross-sectional survey

Malaria Journal • Article: Design matters: structural variation in experimental huts significantly alters entomological endpoints in insecticide treated net (ITN) evaluation –a comparative experimental hut trial using a latin square design in Tanzania and Côte d’Ivoire

Malaria Journal • Perspectives: Health system readiness—the neglected catalyst in Malaria elimination

Malaria Journal • Article: A qualitative study exploring factors associated with the accuracy of recording malaria rapid diagnostic test results in two high-burden regions of Côte d’Ivoire

Malaria Journal • Article: Knowledge, attitudes, and practices of Sudanese medical professionals regarding the 2023 Sudan malaria treatment protocol: a cross-sectional study

Malaria Journal • Article: A target product profile for a rapid diagnostic test to monitor mosquito gene drive presence and frequency

Malaria Journal • Article: The burden of malaria and associated factors among children aged 6–59 months in Mozambique: a nationwide cross‑sectional survey

Malaria Journal • Article: Malaria prevention practice and associated factors among residents in Fogera district, Ethiopia, during the armed conflict between Amhara Fano forces and the federal government, 2025

Malaria Journal • Article: Lumefantrine quantification on pre-treated filter paper dried blood spots for clinical field trials

Malaria Journal • Article: Contemporary Anopheles vector species distribution in Scotland and its association with historical hotspots of malaria transmission

 

Maternal and child health

The BMJ • Practice: Fertility problems: assessment and treatment—summary of updated NICE guidance

 

Neglected tropical diseases

PLOS Neglected Tropical Diseases • Article: A retrospective study on Chagas disease detection and management in Tremedal and Novo Horizonte: Insights prior to the Oxente Chagas Bahia Project

PLOS Neglected Tropical Diseases • Article: PLGA - encapsulated harmine derivative H-2-168: A promising therapeutic agent for mitigating liver damage in hepatic hydatid disease

PLOS Neglected Tropical Diseases • Article: Role of chemokines and their receptors in lesional CD8 T cell homing in Indian Post-Kala-Azar Dermal Leishmaniasis

PLOS Neglected Tropical Diseases • Article: Plasmodium vivax and Plasmodium falciparum mixed infections in human and mosquito hosts: The impact of multi-species infection on parasite densities and transmission to mosquitoes

PLOS Neglected Tropical Diseases • Article: Short-term outcomes of ulnar, median, tibial, and common fibular neurolysis in leprosy neuropathy: A prospective study of pain, sensory function, and muscle strength

PLOS Neglected Tropical Diseases • Article: Trait-based prediction of disease-vector mosquito invasion potential

PLOS Neglected Tropical Diseases • Article: Health education in the prevention and management of infectious diarrhea in childhood: A systematic review of randomized controlled trials

PLOS Neglected Tropical Diseases • Article: Safety and operational feasibility of single versus cocktail rabies monoclonal antibodies for post-exposure prophylaxis in a resource-limited setting

PLOS Neglected Tropical Diseases • Article: Diverse Onchocercidae from Malaysian cats and Indonesian macaques: Morphological and molecular analysis of individual microfilariae using mitochondrial genomes, 28S rRNA, and Wolbachia endosymbiont sequences

PLOS Neglected Tropical Diseases • Article: Neotropical bats as sentinels for emerging zoonoses in Central America: A case study identifying Trypanosoma cruzi in bats from Belize using metagenomic next-generation sequencing

PLOS Neglected Tropical Diseases • Article: Vector competence of Aedes albopictus from Northern, Southeastern, and Southern Brazil for locally circulating East-Central-South African and Asian genotypes of Chikungunya virus

PLOS Neglected Tropical Diseases • Article: First epidemiological characterization of Leishmania tarentolae in sand flies collected in southern France and Corsica Island

PLOS Neglected Tropical Diseases • Article: Brucella outer membrane protein 16 induces trophoblast pyroptosis via rewiring IL-6 trans-signaling and caspase-3/GSDME axis

PLOS Neglected Tropical Diseases • Article: Battling dengue in a warming world: How climate and urbanization shape transmission in low- and middle-income countries (a rapid review)

 

Non-communicable diseases

The Lancet Digital Health • Article: Effectiveness of app-based interventions for glucose management, cardiometabolic and mental health, and related risk factors: an umbrella review with meta-analysis

The Lancet Respiratory Medicine • Comment: Small airways, early origins, and precision prevention of COPD

The Lancet Respiratory Medicine • Article: FEF25–75% trajectories from age 7 to 53 years, associations with childhood and parental preconception factors, and midlife COPD risk: a prospective cohort study

New England Journal of Medicine • Article: Mavacamten for Obstructive Hypertrophic Cardiomyopathy
 

Research and reporting

The Lancet • Comment: Redefining consolidation in primary CNS lymphoma: autologous stem-cell transplantation as the standard

The Lancet • Article: High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial

The Lancet Digital Health • Article: A deep learning model for speech-based prediction of clinical scores in people with Huntington’s disease: a longitudinal study with cross-sectional replication

The BMJ • Opinion: AI might help the NHS—but we need to build the evidence

The BMJ • Feature: China has banned an unproven Alzheimer’s operation and detained its inventor, but international clinical trials of dcLVA are still going ahead—why?

The BMJ • Article: Early treatment with rasburicase and risk of kidney replacement therapy and death in adults with tumour lysis syndrome

The BMJ • Article: Risk of hair loss associated with glucagon-like peptide-1 receptor agonists in adults with type 2 diabetes: target trial emulation

New England Journal of Medicine • Perspectives: When Celebrities Prescribe

New England Journal of Medicine • other: Koebner Phenomenon from Wet Cupping
 

Sexual and reproductive health

The BMJ • Opinion: AI is expanding online sexual abuse against women and girls

 

Vaccines

The Lancet Infectious Diseases • Correspondence: Pseudovirus-based analysis of host cell entry and vaccine-induced neutralisation of Bundibugyo virus

The Lancet Infectious Diseases • Correspondence: SARS-CoV-2 BA.3.2.2 is more evasive of neutralisation by plasma from young children

The Lancet Infectious Diseases • Article: Effectiveness of nirsevimab immunisation on invasive pneumococcal disease in children nationwide in France: an observational cohort study

The Lancet Infectious Diseases • Comment: Reconsidering the rVSVΔG-ZEBOV-GP vaccine during the 2026 Bundibugyo virus outbreak

New England Journal of Medicine • Article: Meningococcal B Vaccine for N. gonorrhoeae Infection