Global health review

MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh. Caption
MSF outreach workers test people for kala azar, Fulbaria, Mymensingh district, Bangladesh.

A weekly round-up of all the latest global health research from MSF projects and beyond

29 March 2024       

This week, to mark World Water Day, MSF contributes to a comment in The Lancet on this year’s theme of Water for Peace. The piece highlights how damage to water stations can disrupt health services, necessitating an interdisciplinary approach for restoration. In JAMA Diabetes & Endocrinology, MSF contributes to an investigation finding that certain insulin medications could be priced lower than they currently are which would contribute to wider access.

 

In Facial Plastic Surgery & Aesthetic Medicine, MSF discusses the outcomes of reconstructive facial surgery for patients with noma and assesses the impact on their quality of life. Meanwhile, research in BMC Health Services Research finds that health professionals commonly utilise routine health data for public health services in the Harari region, Ethiopia. In Toxins, a research article evaluates the tolerance of a snake antivenom under real-life conditions in Cameroon, with results appearing satisfactory. Finally, Open Forum Infectious Disease describes cholera deaths following mass vaccination in Uvira, Democratic Republic of the Congo.

 

Best regards,

 

Lydia Lampiri, Mohammad Salaymeh, Ononna Thuli and Holly Baker with MSF-authored article assistance from Patricia Kahn and Camryn Lewis.

     

All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days International 2023 conference.

 

 

Antimicrobial resistance

 

 

RSTMH Transactions • Article: Antimicrobial resistance genetic determinants and susceptibility profile of Pseudomonas aeruginosa isolated from clinical samples in a tertiary hospital in Ogun State, Nigeria

 

 

 

 

 

Climate change and Planetary Health

 

 

WHO Bulletin • Perspective: A health financing policy agenda for climate mitigation and adaptation

 

 

 

PLOS Global Public Health • Article: Climate change, biodiversity loss, and Indigenous Peoples’ health and wellbeing: A systematic umbrella review

 

 

 

 

WHO Bulletin • Practice: Climate finance opportunities for health and health systems

 

 

 

 

JAMA Network Open • Article: Defining Roles and Responsibilities of the Health Workforce to Respond to the Climate Crisis

 

 

 

 

JAMA Network Open • Opinion: Health Professionals and the Climate Crisis

 

 

 

 

The BMJ • Feature: How climate change is changing vaccination planning

 

 

 

 

 

Conflict, migration and health

 

 

The BMJ • News: “Hospitals should never be battlegrounds,” says WHO amid raids on al-Shifa hospital

 

 

 

Conflict and Halth • Comment: The implications of the Sudan war on healthcare workers and facilities: a health system tragedy

 

 

 

 

 

Global health

 

 

WHO Bulletin • Perspective: A finance and health collaboration to counter pandemic threats

 

 

 

WHO Bulletin • Article: Analysing governments' progress on the right to health

 

 

 

 

WHO Bulletin • Perspective: Beyond GDP: understanding the interdependence of human and planetary health and the economy

 

 

 

 

PLOS Global Public Health • Article: COVID-19 self-testing: Countries accelerating policies ahead of WHO guidelines during pandemics, a global consultation

 

 

 

 

PLOS NTDs • Article: Epidemiological, clinical, and geographical characterization of Leprosy in the County of Santarém-Pará: Insights for effective control and targeted intervention

 

 

 

 

PLOS Global Public Health • Article: Mobilisation towards formal employment in the healthcare system: A qualitative study of community health workers in South Africa

 

 

 

 

BMJ Global Health • Article: Progress towards health equity in Vietnam: evidence from nationwide official health statistics, 2010-2020

 

 

 

 

Facial Plastic Sugery & Aesthetic Medicine • Article***MSF AUTHOR***: Prospective Outcomes of Noma Facial Reconstructive Surgery in Sokoto, Nigeria

 

 

 

 

PLOS Global Public Health • Opinion: Towards authentic institutional allyship by global health funders

 

 

 

 

The Lancet • Comment***MSF AUTHOR***: Water, health, and peace: a call for interdisciplinary research

 

 

 

 

 

HIV

 

 

PLOS Global Public Health • Article: A qualitative analysis of self-management needs of adolescents and young adults living with perinatally acquired HIV in rural, southwestern Uganda

 

 

 

Clinical Infectious Disease • Letter***MSF MENTIONS***: Is Same-Day Antiretroviral Therapy Initiation Beneficial? Methodological Aspects when Comparing Observational and Randomized Studies

 

 

 

 

PLOS Medicine • Article: Long-term HIV care outcomes under universal HIV treatment guidelines: A retrospective cohort study in 25 countries

 

 

 

 

PLOS Global Public Health • Article: Management practices in facilities providing HIV services to key populations in Kenya and Malawi: A descriptive analysis of management in community-based organizations

 

 

 

 

eClinicalMedicine • Article: Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis

 

 

 

 

eBioMedicine • Article: Predictors of liver disease progression in people living with HIV-HBV co-infection on antiretroviral therapy

 

 

 

 

WHO Bulletin • Article: Provision of cervical cancer services for women living with HIV, Uganda

 

 

 

 

PLOS Medicine • Article: Safety and immunogenicity of a subtype C ALVAC-HIV (vCP2438) vaccine prime plus bivalent subtype C gp120 vaccine boost adjuvanted with MF59 or alum in healthy adults without HIV (HVTN 107): A phase 1/2a randomized trial

 

 

 

 

 

Infectious diseases

 

 

eClinicalMedicine • Article***MSF MENTIONS***: Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

 

 

 

Open Forum Infectious Diseases • Article***MSF MENTIONS***: Cholera Deaths During Outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10–35 Months After Mass Vaccination

 

 

 

 

RSTMH Transactions • Article: Comparison of miRNA profiles in the immune response of pediatric acute appendicitis and pediatric enterobiasis patients caused by Enterobius vermicularis

 

 

 

 

PLOS Global Public Health • Article: Predictors to Intensive Care Unit admission among patient with coronavirus disease in Sukraraj Tropical and Infectious Disease Hospital, Nepal: A case-control study

 

 

 

 

 

Malaria

 

 

Malaria Journal • Article: Cerebral malaria presenting as nonconvulsive status epilepticus: a case report

 

 

 

Malaria Journal • Article: Community and health worker perspectives on malaria in Meghalaya, India: covering the last mile of elimination by 2030

 

 

 

 

Malaria Journal • Article: Malaria infection among adults residing in a highly endemic region from the Democratic Republic of the Congo

 

 

 

 

BMJ Global Health • Article: Reduction of malaria case incidence following the introduction of clothianidin-based indoor residual spraying in previously unsprayed districts: an observational analysis using health facility register data from Côte d’Ivoire, 2018–2022

 

 

 

 

Malaria Journal • Article: The effect of COVID-19 on malaria cases in Zambia: a mixed effect multilevel analysis

 

 

 

 

 

Maternal and child health

 

 

eBioMedicine • Article: Co-occurrence of and factors associated with health risk behaviors among adolescents: a multi-center study in sub-Saharan Africa, China, and India

 

 

 

The Lancet Regional Health-Southeast Asia • Article: Effect of a parenting and nutrition education programme on development and growth of children using a social safety-net platform in urban Bangladesh: a cluster randomized controlled trial

 

 

 

 

The Lancet Global Health • Article: Effectiveness of bubble continuous positive airway pressure for treatment of children aged 1–59 months with severe pneumonia and hypoxaemia in Ethiopia: a pragmatic cluster-randomised controlled trial

 

 

 

 

PLOS Global Public Health • Article: Experiences of teachers and students on school closures and its consequences during the COVID-19 pandemic in Nyarugusu refugee camp, Tanzania

 

 

 

 

The Lancet • Article: Outcomes after surgery for children in Africa (ASOS-Paeds): a 14-day prospective observational cohort study

 

 

 

 

PLOS Global Public Health • Article: Predictors of neonatal mortality in Ethiopia: Cross sectional study using 2005, 2010 and 2016 Ethiopian demographic health survey datasets

 

 

 

 

SSM - Qualitative Research in Health • Article***MSF & EPICENTRE MENTIONS***: Reasons for delay in reaching healthcare with severe abortion-related morbidities: Qualitative results from women in the fragile context of Jigawa state, Nigeria (AMoCo)

 

 

 

 

PLOS Global Public Health • Article: The WHO atlas for female-genital schistosomiasis: Co-design of a practicable diagnostic guide, digital support and training

 

 

 

 

PLOS Global Public Health • Article: Validation of the Emergency Department-Paediatric Early Warning Score (ED-PEWS) for use in low- and middle-income countries: A multicentre observational study

 

 

 

 

 

Mental health

 

 

JAMA Pediatrics • Article: Mental Health of Adolescents Exposed to the War in Ukraine

 

 

 

WHO Bulletin • Practice: Towards a well-being economy for mental health

 

 

 

 

 

Neglected tropical diseases

 

 

WHO Bulletin • Article: Age-group associations of schistosomiasis prevalence from trial data, Côte d’Ivoire, Kenya and the United Republic of Tanzania

 

 

 

The Lancet Infectious Diseases • Article: Effect of single-dose, live, attenuated dengue vaccine in children with or without previous dengue on risk of subsequent, virologically confirmed dengue in Cebu, the Philippines: a longitudinal, prospective, population-based cohort study

 

 

 

 

PLOS NTDs • Article: Harnessing Schistosoma-associated metabolite changes in the human host to identify biomarkers of infection and morbidity: Where are we and what should we do next?

 

 

 

 

PLOS NTDs • Article: Impact of annual community-directed treatment with ivermectin on the incidence of epilepsy in Mvolo, a two-year prospective study

 

 

 

 

RSTMH Transactions • Article: Motivation–opportunity–ability–behaviour of community members and program implementers towards mass drug administration for lymphatic filariasis elimination in India: a systematic review and implementation priority

 

 

 

 

PLOS NTDs • Article: Sero-prevalence and risk factors associated with occurrence of anti-Brucella antibodies among slaughterhouse workers in Uganda

 

 

 

 

Toxins • Article***EPICENTRE MENTIONS***: Snakebites in Cameroon: Tolerance of a Snake Antivenom (Inoserp™ PAN-AFRICA) in Africa in Real-Life Conditions

 

 

 

 

RSTMH Transactions • Article: Spatial-temporal distribution of visceral leishmaniasis in Rio de Janeiro, Brazil, 2001–2020: expansion and challenges

 

 

 

 

WHO Bulletin • Practice: Target product profiles: leprosy diagnostics

 

 

 

 

PLOS NTDs • Article: The role of point-of-care ultrasound in the assessment of schistosomiasis-induced liver fibrosis: A systematic scoping review

 

 

 

 

 

Non-communicable diseases

 

 

JAMA Diabetes and Endocrinology • Article***MENTIONS MSF***: Estimated Sustainable Cost-Based Prices for Diabetes Medicines

 

 

 

The Lancet Regional Health-Southeast Asia • Article: Preliminary results of hypofractionated radiotherapy in breast cancer in Chandigarh, India: single-centre, non-inferiority, open-label, randomised, phase 3 trial

 

 

 

 

PLOS Global Public Health • Article: Social network enhanced behavioral interventions for diabetes and obesity: A 3 arm randomized trial with 2 years follow-up in Jordan

 

 

 

 

Tropical Medicine and International Health • Article: Transfers between health facilities of people living with diabetes attending primary health care services in the Western Cape Province of South Africa: A retrospective cohort study

 

 

 

 

 

Outbreaks

 

 

PLOS Glboal Public Health • Article: A time of decline: An eco-anthropological and ethnohistorical investigation of mpox in the Central African Republic

 

 

 

BMJ Global Health • Article: Building citizen science intelligence for outbreak preparedness and response: a mixed-method study in nine countries to assess knowledge, readiness and feasibility

 

 

 

 

WHO Bulletin • Review: Financing for pandemic preparedness and response measures: a systematic scoping review

 

 

 

 

 

Research and reporting

 

 

PLOS Global Public Health • Article: Adaptation of the Client Diagnostic Questionnaire for East Africa

 

 

 

BMJ Global Health • Article: Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study

 

 

 

 

PLOS Global Public Health • Article: Anaesthesia delivery systems in low and lower-middle-income Asian countries: A scoping review of capacity and effectiveness

 

 

 

 

PLOS Global Public Health • Article: Assessing the influence of COVID-19 lockdown measures on cognition and behavior in school age children in Arba Minch Health and Demographic Surveillance site, Southern Ethiopia: A cross-sectional study

 

 

 

 

eClinicalMedicine • Article: Clinical spectrum and evolution of immune-checkpoint inhibitors toxicities over a decade—a worldwide perspective

 

 

 

 

PLOS Global Public Health • Article: Exploring different health care providers´ perceptions on the management of diarrhoea in cholera hotspots in the Democratic Republic of Congo: A qualitative content analysis

 

 

 

 

The Lancet • Article: Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

 

 

 

 

WHO Bulletin • Article: Improving the management of open tibia fractures, Malawi

 

 

 

 

PLOS Global Public Health • Article: Leveraging qualitative approaches to guide sustainable international research collaborations

 

 

 

 

BMC Health Services Research • Article***MSF MENTIONS***: Utilization of routine health data and its determinants among healthcare workers in public health facilities of harari region, eastern Ethiopia

 

 

 

 

 

Tuberculosis

 

 

eClinicalMedicine • Article: Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study

 

 

 

eClinicalMedicine • Article***EPICENTRE MENTIONS***: Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study

 

 

 

 

eClinicalMedicine • Article: Effect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study

 

 

 

 

The Lancet Infectious Diseases • Article: Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021

 

 

 

 

PLOS Medicine • Article: Quantifying gaps in the tuberculosis care cascade in Brazil: A mathematical model study using national program data

 

 

 

 

Clinical Infectious Disease • Article***MSF MENTIONS***: The Safety and Tolerability of Linezolid in Novel Short-Course Regimens Containing Bedaquiline, Pretomanid, and Linezolid to Treat Rifampicin-Resistant Tuberculosis: An Individual Patient Data Meta-analysis

 

 

 

 

 

Vaccines

 

 

Vaccine X • Comment***EPICENTRE MENTIONS***: A conceptual framework to model social determinants of COVID-19 vaccination uptake among underserved homeless populations

 

 

 

PLOS Global Public Health • Article: Cross-sectional study on intention to be vaccinated against Coronavirus Disease 2019 (COVID-19) in Benin and Senegal: A structural equation modeling (SEM)

 

 

 

 

WHO Bulletin • Article: Global vaccine coverage and childhood survival estimates; 1990–2019

 

 

 

 

The Lancet Infectious Diseases • Article: Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial

 

 

 

 

 

Zika

 

 

PLOS NTDs • Article: Assessing vulnerability for future Zika virus outbreaks using seroprevalence data and environmental suitability maps